Khoury started his professional career soon after his graduate studies in post-war Beirut, which became his territory of experimentation where he produced 16 unbuilt projects spanning a period of four years (1993-1997). During the early years of his practice, he was financially supported by his family’s furniture manufacturing business that provided him with a design studio and gave him access to the workshop and manufacturing facilities of their factories. Khoury first came to public and critical attention with the completion of the B018 music club in 1998, his first built project. This building sparked a string of temporary projects, through which Khoury built a reputation for his ability to produce critical interventions in problematic zones. These include his first six built projects: the Centrale project (2000), Yabani (2001), the BLC Bank (2004), the Bank of Beirut pavilion in Chtaura (2005), as well as the Black Box (2005). In the media, various publications dubbed Khoury "the bad boy" of architecture in the Middle East. Khoury's early clients came primarily from the entertainment industry. He then produced projects for local banks. His first international commission, the Pfefferberg Project, was in Berlin, Germany (1999-2001) and consisted of the conversion of an industrial block into a cultural quarter. Aborted commissions followed in Europe, including the Santa Cesarea project in Italy (2007), as well as residential projects in England, Spain and Serbia. He then worked on commissions such as the Tumo Center for Creative Technologies (2011), the Tumo Park (2011) and the Epygi Park Master Plan (2013) in Yerevan, Armenia, as well as the AGBU NKR Campus (2014) in Nagorno-Karabakh. He has also worked in the Arab world. These comprise schemes in the Arabian Gulf region, such as the Fintas Market (2003) and the Andalus Development (2006) in Kuwait; the Alargan Business Bay Development (2006) and the Ajman Resort (2012-2013) in the United Arab Emirates; Al Qurm Mixed Use Development (2012) in Oman; Surramanraa (2005) in Riyadh; and the Suspended Gardens of Manama (2011) in Bahrain. Khoury’s first permanent building, IB3, was completed in 2006. IB3 was followed by Plot # 732 (2008), Plot # 183 (2009) and Plot # 893 (2010), all of which engage their surrounding urban fabric. These were followed by the developments on Plots # 1314 and 2251 (2013) in Beirut, in which Khoury designed his own residence. Plot # 4371 (2009), a more recent residential project, allows its inhabitants to move their vehicles vertically within the buildings to park them in the center of their living room. Plot # 1282 (2010, also known as Factory Lofts) is characterized by its thin slabs and openness on all orientations, stretching over 166 meters in length with a perimeter of 430 linear meters. Plot # 1072 (2009, also known as the Skyline), Plot # 1342 (2010, also known as the Paramount) and Plot # 450 (2014, also known as the Grand Hotel de Beirut) are high rise residential developments. On a smaller scale, a number of Khoury's projects were produced mainly in the mountainous regions of Lebanon, including Plot # 7950 (2010), which houses 52 engines that operate its retractable roof, and Plot # 4328 (2010) with an accessible inclined façade culminating in a linear lap pool.